Roohi Khan is counted among few of the most senior actresses who are actively participating as a TV artist. One of her early performances came in the Pakistan Television (PTV) drama serial 'Bulandi', which was produced by Kashif Mehmood. The drama received a lot of appreciation and Roohi's performance was duly appreciated by the TV viewers.
Her later performances came in the dramas made for private TV channels. In the past few years, one of her most popular drama serials has been 'Reshmi', which was aired on Geo TV. The drama was a sitcom and was appreciated for its humor as well as performances. Another one of her famous drama serials was 'Adhuri Film Ki Puri Kahani', which was shown on ATV.
As an actress, she did not limit her creativity and has worked in dramas that allowed her to fully display her acting skills. Her most recent performances include 'Dil, Dubai, Sehra', which also aired on ATV and 'Daasi', which was shown on A Plus.